1.Kaplan and Sadock Psikiyatri Özeti
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Giriş Yapın3. Yeni Oxford Psikiyatri
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Hemin R Chin, Steven O Moldin
CRC Press; 2001; pp344; ISBN: 0849323975
Methods and New Frontiers in Neuroscience, Volume: 10
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5. Cognitive Neuroscience of Aging: Linking Cognitive and Cerebral Aging
Publisher: Oxford University Press, USA
Number Of Pages: 408
Publication Date: 2004-10-22
Sales Rank: 770596
ISBN / ASIN: 0195156749
EAN: 9780195156744
Binding: Hardcover
Manufacturer: Oxford University Press, USA
Studio: Oxford University Press, USA
Average Rating: 0
Total Reviews: 0
Book Description:
Until very recently, our knowledge about the neural basis of cognitive aging was based on two disciplines that had very little contact with each other. Whereas the neuroscience of aging investigated the effects of aging on the brain independently of age-related changes in cognition, the cognitive psychology of aging investigated the effects of aging on cognition independently of age-related changes in the brain. The lack of communication between these two disciplines is currently being addressed by an increasing number of studies that focus on the relationships between cognitive aging and cerebral aging. This rapidly growing body of research has come to constitute a new discipline, which may be called cognitive neuroscience of aging. The goal of Cognitive Neuroscience of Aging is to introduce the reader to this new discipline at a level that is useful to both professionals and students in the domains of cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology, neurology, and other, related areas. This book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiologica
l (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging on neural activity during different cognitive functions, including perception and attention, imagery, working memory, long-term memory, and prospective memory. The third section focuses on clinical and applied topics, such as the distinction between healthy aging and Alzheimers disease and the use of cognitive training to ameliorate age-related cognitive decline. The last section describes theories that relate cognitive and cerebral aging, including models accounting for functional neuroimaging evidence and models supported by computer simulations. Taken together, the chapters in this volume provide the first unified and comprehensive overview of the new discipline of cognitive neuroscience of aging.
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6.
Evolutionary Cognitive Neuroscience
By
Publisher: The MIT Press
Number Of Pages: 620
Publication Date: 2006-11-01
Sales Rank: 350575
ISBN / ASIN: 0262162415
EAN: 9780262162418
Binding: Hardcover
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 4
Total Reviews: 1
Book Description:
Since Darwin we have known that evolution has shaped all organisms and that biological organs--including the brain and the highly crafted animal nervous system--are subject to the pressures of natural and sexual selection. It is only relatively recently, however, that the cognitive neurosciences have begun to apply evolutionary theory and methods to the study of brain and behavior. This landmark reference documents and defines the emerging field of evolutionary cognitive neuroscience. Chapters by leading researchers demonstrate the power of the evolutionary perspective to yield new data, theory, and insights on the evolution and functional modularity of the brain.
Evolutionary cognitive neuroscience covers all areas of cognitive neuroscience, from nonhuman brain-behavior relationships to human cognition and consciousness, and each section of Evolutionary Cognitive Neuroscience addresses a different adaptive problem. After an introductory section that outlines the basic tenets of both theory and methodology of an evolutionarily informed cognitive neuroscience, the book treats neuroanatomy from ontogenetic and phylogenetic perspectives and explores reproduction and kin recognition, spatial cognition and language, and self-awareness and social cognition. Notable findings include a theory to explain the extended ontogenetic and brain development periods of big-brained organisms, fMRI research on the neural correlates of romantic attraction, an evolutionary view of sex differences in spatial cognition, a theory of language evolution that draws on recent research on mirror neurons, and evidence for a rudimentary theory of mind in nonhuman primates. A final section discusses the ethical implications of evolutionary cognitive neuroscience and the future of the field.
Contributors:
C. Davison Ankney, Simon Baron-Cohen, S. Marc Breedlove, William Christiana, Michael Corballis, Robin I. M. Dunbar, Russell Fernald, Helen Fisher, Jonathan Flombaum, Farah Focquaert, Steven J. C. Gaulin, Aaron Goetz, Kevin Guise, Ruben C. Gur, William D. Hopkins, Farzin Irani, Julian Paul Keenan, Michael Kimberly, Stephen Kosslyn, Sarah L. Levin, Lori Marino, David Newlin, Ivan S. Panyavin, Shilpa Patel, Webb Phillips, Steven M. Platek, David Andrew Puts, Katie Rodak, J. Philippe Rushton, Laurie Santos, Todd K. Shackelford, Kyra Singh, Sean T. Stevens, Valerie Stone, Jaime W. Thomson, Gina Volshteyn, Paul Root Wolpe
Date: 2007-08-04 Rating: 4
Review:
diverse topics for an exciting science
It is an exciting time in neuroscience. As the realisation dawned in recent years that evolutionary ideas can be fruitfully applied to the brains of various species. Along with the experimental tools that enable the testing of useful models of the brain.
The book's diversity of papers reflects accurately the intellectual ferment. One example might be the rise of evolutionary game theory. Standard game theory arose with von Neumman and others, and was originally only applied to human subjects. But a chapter on SPFit delves into how players evolve in geological time, optimising their reproductive odds. Thus the promise is to see how behaviour can be explained in the context of playing a long game.
Another very topical issue in the book is mirror neurons. Covered all too briefly here, given the amount of research that is ongoing. If there will ever be another edition of this book, perhaps more space could be allocated to it?
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Cognitive Neuroscience of Emotion
By
Publisher: Oxford University Press, USA
Number Of Pages: 431
Publication Date: 2000-01-15
Sales Rank: 1424712
ISBN / ASIN: 019511888X
EAN: 9780195118889
Binding: Hardcover
Manufacturer: Oxford University Press, USA
Studio: Oxford University Press, USA
Average Rating: 4
Total Reviews: 1
Book Description:
This book, a member of the Series in Affective Science, is a unique interdisciplinary sequence of articles on the cognitive neuroscience of emotion by some of the most well-known researchers in the area. It explores what is known about cognitive processes in emotion at the same time it reviews the processes and anatomical structures involved in emotion, determining whether there is something about emotion and its neural substrates that requires they be studied as a separate domain. Divided into four major focal points and presenting research that has been performed in the last decade, this book covers the process of emotion generation, the functions of amygdala, the conscious experience of emotion, and emotion regulation and dysregulation. Collectively, the chapters constitute a broad but selective survey of current knowledge about emotion and the brain, and they all address the close association between cognitive and emotional processes. By bringing together diverse strands of investigation with the aim of documenting current understanding of how emotion is instantiated in the brain, this book will be of use to scientists, researchers, and advanced students of psychology and neuroscience.
Date: 2002-07-31 Rating: 4
Review:
Great.
Emotion had been largely ignored in cognitive neuroscience until some year ago (with LeDoux, Damasio, Panksepp leading the way) Now, there are various attempts to restore emotion as a very important and fruitfull line of research. Cognition cannot be understood stripped of emotion. This book is a collection of the many issues in affective neuroscience. There are various papers dealing with its neuronal correlates, its place in the cognitive hierarchy, with value, its conscious expression, among many other things. Emotion is a complex and multifaceted phenomenon, and cognitive neuroscience is trying to explain it from many prespectives. This book is the culmination of these attempts. Must-read for anyone interested in emotion and neuroscience.
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Handbook of Developmental Cognitive Neuroscience (Developmental Cognitive Neuroscience)
By
Publisher: The MIT Press
Number Of Pages: 685
Publication Date: 2001-04-02
Sales Rank: 688784
ISBN / ASIN: 026214073X
EAN: 9780262140737
Binding: Hardcover
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 5
Total Reviews: 1
Book Description:
The publication of this handbook testifies to the rapid growth of developmental cognitive neuroscience as a distinct field. Brain imaging and recording technologies, along with well-defined behavioral tasks--the essential methodological tools of cognitive neuroscience--are now being used to study development. Whereas earlier methodologies allowed scientists to study only adult brains, recent technological advances have yielded methods that can be safely used to study structure-function relations and their development in children's brains. These new techniques combined with more refined cognitive models account for the progress and heightened activity in developmental cognitive neuroscience research.
The handbook contains forty-one original contributions exploring basic aspects of neural development, sensory and sensorimotor systems, language, cognition, and emotion. Aided by recent results in neurobiology establishing that the human brain remains malleable and plastic throughout much of the lifespan, the contributors also explore the implications of lifelong neural plasticity for brain and behavioral development.
This book is also available online as part of MIT CogNet, The Cognitive and Brain Sciences Community online.
Date: 2003-01-08 Rating: 5
Review:
Development and Cognitive Neurscience finally come together!
I have long been awaiting a comprehensive text on developmental cognitive neuroscience. This book contains 41 superb articles, convering a variety of areas from neurobiology to language and cognition. It is a very good book for those wanting a quick introduction to this field. A very enjoyable book to read!
PDF, 70.6 MB
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Neuropsychiatry and Behavioral Neuroscience
By Jeffrey L. Cummings, Michael S. Mega,
Publisher: Oxford University Press, USA
Number Of Pages: 432
Publication Date: 2003-01-21
Sales Rank: 678595
ISBN / ASIN: 0195138589
EAN: 9780195138580
Binding: Hardcover
Manufacturer: Oxford University Press, USA
Studio: Oxford University Press, USA
Average Rating: 3.5
Total Reviews: 2
Book Description:
This is the long-awaited successor to Jeffrey Cummings' classic work, Clinical Neuropsychiatry, published in 1985. That book represented an integration of behavioral neurology and biological psychiatry into a single volume devoted to explicating brain-behavior relationships. It was clinically oriented and intended for practitioners caring for patients with neuropsychiatric disorders. The new title reflects the authors' effort to link the recent explosion of new information from neurochemistry, neuroanatomy, genetics, neuropharmacology, neuropathology, and neuroimaging to the clinical descriptions. Yet the clinical emphasis of its predecessor has been maintained. Each chapter has a consistent approach and the book as whole provides a practical, easy-to-use synthesis of clinical advice and basic science. The volume is enhanced by 4-color images throughout. It is intended for students, residents, fellows, and practitioners of neurology, psychiatry, neuropsychology, and cognitive neuroscience. It will also be of interest to individuals in neuroimaging.
Date: 2007-01-15 Rating: 4
Review:
Easy to read
Very interenting form to present Human behavior as a biological perspective. Easy to read this very scientific knowledge. Perhaps the only "but" is one chapter about "conciouness".
Date: 2006-04-09 Rating: 3
Review:
Excellent in places
I tend to read a lot of neuropsychiatry books for work and this is the latest from Jeff Cummings - an author who seems to do little wrong! The production value on this book is very high - quite a few color illustrations are used. The text is, in general, sensible and useful but there are some minor inaccuracies and some topics not covered. In places the depth is not really adequate and it may not offer quite the same coverage as competing volumes. Overall, excellent in places, but some omissions - therefore I would give it ok(3stars). I am sure the next edition, will offer more.
CHM 14.4 MB
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Biomedical Imaging in Experimental Neuroscience (Methods and New Frontiers in Neuroscience)
By
Publisher: CRC
Number Of Pages: 368
Publication Date: 2002-12-23
Sales Rank: 1928334
ISBN / ASIN: 084930122X
EAN: 9780849301223
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Average Rating: 0
Total Reviews: 0
Book Description:
Recent years have seen an explosion of activity in the field of biomedical imaging in an attempt to understand the behavior of the brain in healthy and disease states. With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting new era with revolutionary tools for experimental research. Noninvasive imaging techniques capable of providing both anatomical and functional descriptions of the brain have become essential. Among the various imaging methodologies, magnetic resonance imaging (MRI) stands in the forefront by virtue of its contrast versatility and pathophysiological specificity. Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the noninvasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book is intended for the biologist who may not have a background in the physical sciences. This applied guide also provides a concise theoretical description of the pertinent physics. Noninvasive imaging offers the obvious benefits of reducing sample sizes and identifying new and unanticipated behaviors. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings and disease pathophysiology.
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Computational Neuroscience: A Comprehensive Approach (Chapman & Hall/Crc Mathematical Biology & Medicine Series)
By
Publisher: Chapman & Hall/CRC
Number Of Pages: 656
Publication Date: 2003-10-20
Sales Rank: 1293365
ISBN / ASIN: 1584883626
EAN: 9781584883623
Binding: Hardcover
Manufacturer: Chapman & Hall/CRC
Studio: Chapman & Hall/CRC
Average Rating: 0
Total Reviews: 0
Book Description:
How does the brain work? After a century of research, we still lack a coherent view of how neurons process signals and control our activities. But as the field of computational neuroscience continues to evolve, we find that it provides a theoretical foundation and a set of technological approaches that can significantly enhance our understanding. Computational Neuroscience: A Comprehensive Approach provides a unified treatment of the mathematical theory of the nervous system and presents concrete examples demonstrating how computational techniques can illuminate difficult neuroscience problems. In chapters contributed by top researchers, the book introduces the basic mathematical concepts, then examines modeling at all levels, from single-channel and single neuron modeling to neuronal networks and system-level modeling. The emphasis is on models with close ties to experimental observations and data, and the authors review application of the models to systems such as olfactory bulbs, fly vision, and sensorymotor systems. Understanding the nature and limits of the strategies neural systems employ to process and transmit sensory information stands among the most exciting and difficult challenges faced by modern science. This book clearly shows how computational neuroscience has and will continue to help meet that challenge.
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From NEUROSCIENCE To NEUROLOGY: Neuroscience, Molecular Medicine, and the Therapeutic Transformation of Neurology
By Stephen Waxman
Publisher: Academic Press
Number Of Pages: 552
Publication Date: 2004-10-18
Sales Rank: 1764565
ISBN / ASIN: 0127389032
EAN: 9780127389035
Binding: Hardcover
Manufacturer: Academic Press
Studio: Academic Press
Average Rating: 0
Total Reviews: 0
Book Description:
The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinsons disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord.
The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone clinicians and basic scientists alike interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders.
* Presents the evolution of the field of neurology into a therapeutic discipline
* Discusses lessons learned from past successes and applications to ongoing work
* Explores the future of this field
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13.
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By
Publisher: Academic Pr
Number Of Pages: 440
Publication Date: 1995-03
Sales Rank: 5025618
ISBN / ASIN: 0126192553
EAN: 9780126192551
Binding: Paperback
Manufacturer: Academic Pr
Studio: Academic Pr
Average Rating: 0
Total Reviews: 0
Book Description:
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike.
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Psychoanalysis and Neuroscience
By
Publisher: Springer
Number Of Pages: 436
Publication Date: 2006-09-14
Sales Rank: 1542459
ISBN / ASIN: 8847003342
EAN: 9788847003347
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating: 0
Total Reviews: 0
Book Description:
The most recent scientific studies have brought a significant contribution to the understanding of basic mental functions such as memory, dreams, identification, repression, which constitute the basis of the psychoanalytical theory. As a matter of fact, numerous neuroscientific observations in recent years have laid the ground for hypotheses on the neurological organization of mental functions that are fundamental to psychoanalytical theory; the discovery of the implicit memory has extended Freuds concept of the unconscious (1915) and highlighted the unrepressed unconscious connected particularly to experiences of the primary relation, stored in the implicit memory.
The book focuses on the possibility of interactions between psychoanalysis and neuroscience - i.e., emotions and the right hemisphere, serotonin and depression - and will be a unique tool not only for for professionals and students working in these fields, but also for operators of allied disciplines, such as psychology and psychotherapy.
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Mental Mechanisms: Philosophical Perspectives on Cognitive Neuroscience
By William Bechtel
Publisher: Lawrence Erlbaum
Number Of Pages: 328
Publication Date: 2007-10-29
Sales Rank: 3560155
ISBN / ASIN: 0805863338
EAN: 9780805863338
Binding: Hardcover
Manufacturer: Lawrence Erlbaum
Studio: Lawrence Erlbaum
Average Rating: 0
Total Reviews: 0
Book Description:
A variety of scientific disciplines have set as their task explaining mental activities, recognizing that in some way these activities depend upon our brain. But, until recently, the opportunities to conduct experiments directly on our brains were limited. As a result, research efforts were split between disciplines such as cognitive psychology, linguistics, and artificial intelligence that investigated behavior while disciplines such as neuroanatomy, neurophysiology, and genetics experimented on the brains of non-human animals. In recent decades these disciplines integrated, and with the advent of techniques for imaging activity in human brains, the term cognitive neuroscience has been applied to the integrated investigations of mind and brain. This book is a philosophical examination of how these disciplines continue in the mission of explaining our mental capacities.
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Neuroscience and Philosophy: Brain, Mind, and Language
By Maxwell Bennett, Daniel Dennett, Peter HOaOcOkOeOr, John Searle,
Publisher: Columbia University Press
Number Of Pages: 232
Publication Date: 2007-03-15
Sales Rank: 195044
ISBN / ASIN: 0231140444
EAN: 9780231140447
Binding: Hardcover
Manufacturer: Columbia University Press
Studio: Columbia University Press
Average Rating: 4
Total Reviews: 1
Date: 2007-06-01 Rating: 4
Review:
science intersecting with philosophy
Philosophy is one of the oldest intellectual pursuits. Yet it is only in very recent times that science is starting to provide an underpinning. The status of this is argued in this book. With some of the latest results and trends in neuroscience as the talking point.
The book is formatted with 2 scientists providing views on consciousness, as gleaned from experiments. While the contrary opinions are given by 2 philosophers. With the scientists then given space to issue a reply.
Whatever your own positions on all this, perhaps you can appreciate the excitement in the air. For the first time, philosophy has hard experimental observations to cogit over. And the problem of consciousness is surely one of the fundamental unknowns in science.
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Cellular and Molecular Methods in Neuroscience Research
By
Publisher: Springer
Number Of Pages: 336
Publication Date: 2002-10-01
Sales Rank: 1401089
ISBN / ASIN: 0387953868
EAN: 9780387953861
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating: 0
Total Reviews: 0
Book Description:
Analysis of the neural tissue presents unique and peculiar technical problems encountered in everyday bench work. Numerous books dealing with cellular and molecular protocols for general use in cell biology are available, but few are specifically devoted exclusively to neurobiology. Moreover, the "cross-talk" between researchers with different backgrounds, i.e. histologists, cell and molecular biologists and physiologists, is still quite difficult, and very often one remains somehow "confined" to his or her own specific field of expertise never daring to explore "mysterious" lands unless having the support of a big laboratory beyond. The general idea beyond this project was to put together the contributions from a number of well-known neuroscientists to produce a book that offers a survey of the most updated techniques for the study of nerve cells. After a long time spent doing research in the neuroscience field, and having acquired a good technical background in certain specific fields of neurobiology we have realized how difficult is to be able to step into a different technology. This book endeavors to assist in that goal.
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Neural Development and Stem Cells (Contemporary Neuroscience)
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Publisher: Humana Press
Number Of Pages: 468
Publication Date: 2005-09-15
Sales Rank: 1413048
ISBN / ASIN: 1588294811
EAN: 9781588294814
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:
This extensively expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system. Working from a new understanding that the regionalization of stem cells occurs early in development and that this bias appears to persist even after prolonged culture, Dr. Rao has added additional chapters on olfactory epithelial stem cells and retinal stem cells, both of which differ in their properties from ventricular zone and subventricular zone-derived neural stem cells. A new chapter on cell death summarizes the important changes in the death pathway that occurs as stem cells mature. Special attention is paid to the derivation of neural cells from embryonic stem cells. Authoritative and up-to-date, Neural Development and Stem Cells, Second Edition provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.
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Mitochondrial Inhibitors and Neurodegenerative Disorders (Contemporary Neuroscience)
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Publisher: Humana Press
Number Of Pages: 360
Publication Date: 1999-10-01
Sales Rank: 2481588
ISBN / ASIN: 089603805X
EAN: 9780896038059
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 5
Total Reviews: 1
Book Description:
Respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers-many pioneers in the field-detail the symptomology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The emphasis on 3-NP and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease demonstrate that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. The book also discusses recent therapeutic modalities aimed at rescuing the central nervous system from abnormal mitochodrial functioning. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression.
Date: 1999-12-05 Rating: 5
Review:
Excellent neuroscience research book.
For those interested in research on neurodegeneration, this book provides compelling evidence of the effects of mitochondrial impairment on cell death. The book covers specialty topics including animal models of neurological disorders and novel repair strategies conducted by leading scientists around the world.
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24.
Theoretical Neuroscience: Computational and Mathematical Modeling of Neural Systems
By Peter Dayan, L. F. Abbott,
Publisher: The MIT Press
Number Of Pages: 480
Publication Date: 2005-09-01
Sales Rank: 120962
ISBN / ASIN: 0262541858
EAN: 9780262541855
Binding: Paperback
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 4
Total Reviews: 6
Book Description:
Theoretical neuroscience provides a quantitative basis for describing what nervous systems do, determining how they function, and uncovering the general principles by which they operate. This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory.
The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.
Date: 2007-01-28 Rating: 5
Review:
Good book for computational neuroscience
I am a mathematician and economist interested in how human brain works. To me, (so far) this is the best book using equations to describe the overall picture of brain functions. Even though it might not touch in-depth research topics, I am sure it gives anyone interested in neuroscience very solid foundations on which more advance topics are built. (It actually invites me to more in-depth research topics, such as reinforcement learning, reward-punishment system, etc.)
If math is your familiar language (says, system of differential equations and Bayesian probability), and you are interested to know, in technical details, how the brain functions, this book is for you. Then, I think, you can go into research topics of your interests after finishing reading this book.
Date: 2006-03-23 Rating: 4
Review:
"Theoretical Neuroscience" Dry but Informative
"Theoretical Neuroscience" is an in-depth introduction to modeling of neural systems from the chemical/electrical processes within neurons, up through small networks of neurons. It is a little dry, but provides a wealth of information on modeling the electrophysical and computational properties of neurons.
Date: 2005-07-05 Rating: 2
Review:
Good starting point for undergraduate students
This book covers a wide range of different and important subjects of this field and provides by this a good overview to students new in neuroscience. On the other hand side, the topics discussed are not described thoroughly, but stay on the surface. This maybe no big problem for undergraduates who try just to understand the basics but certainly this is not satisfactory for more advanced students or researches.
In my opinion, this book blurs the view of the reader by presenting results about experiments and theoretical models side by side in a way that no fair and solid discussion is provided indicating clearly the limitations and problems of current models. By this, one could get the feeling that the presented models are more than tool to analyse data. However, exactly this is not true for most of the models as can be seen by the fact that these models can also be found in other areas than neuroscience with other interpretations.
Date: 2004-06-11 Rating: 4
Review:
Theoretical Neurosciences from a Computational Perspective
This text will become a standard course book for Graduate Schools in Computational Neurosciences. You need to know advanced engineering mathematics & probability theory to be able to understand this book. Dayan & Abbott model primary visual cortical, MT, LIP, and Motor cortical neurons as single units, but also as populations (clusters) of firing cells. They discuss Bayes Theorem, probability theory as it applies to the brain, and parietal lobe function as well. They derive all the equations associated with these models for the student so that more advanced parts of the book are comprehensible. The book is not meant to be a general Neuroscience book, but rather a course book about neuronal modeling, computational neurobiology, and neural engineering. It serves these three purposes well. In my opinion, this is the best written account of neuron modeling out there for the graduate student and researcher. Methods in Neuronal Modeling by Christof Koch is the other great book on this subject. If you own these two books you should be able to advance in high level neural modelling. There are numerous equations and formulae of interest throughout each chapter in these two volumes. The price of 39.00 USD for the hardcover is really quite a bargain.
Date: 2003-08-16 Rating: 5
Review:
Great textbook and reference
This book is certainly the most thorough textbook currently available
on many aspects of computational neuroscience. It works very carefully
through the fundamental assumptions and equations underlying large
tracts of contemporary quantitative analysis in neuroscience. It is
an ideal introductory book for those with a quantitative background,
and is destined to become a standard course book in the field.
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Astrocytes in Brain Aging and Neurodegeneration (Neuroscience Intelligence Unit)
By Hyman M., Ed. Schipper
Publisher: LANDES BIOSCIENCE PUBLISHERS
Number Of Pages: 256
Publication Date: 1998-09-15
Sales Rank: 5222722
ISBN / ASIN: 1570594899
EAN: 9781570594892
Binding: Hardcover
Manufacturer: LANDES BIOSCIENCE PUBLISHERS
Studio: LANDES BIOSCIENCE PUBLISHERS
Average Rating: 0
Total Reviews: 0
Book Description:
256 pages, 67 figures, 6 tables, hardcover This monograph is the first of its kind to focus specifically on the role of astroglia in aging-related human neurodegenerative disorders and experimental models of CNS senescence and degeneration. As such, this volume in the Neuroscience Intelligence Unit Series represents a novel and important contribution to the basic and clinical neuroscience literature. The chapters are grouped into three sections: I. Biology of Astrocytes. The chapters in this section will constitute a comprehensive discussion of the known functions of astroglia in the mammalian CNS and the roles these cells may play in the pathophysiology of neurological disorders. II. Astrocytes in Human Brain Senescence and Neurodegenerative Disorders. In this section, the pathology of astrocytes and their putative roles in human CNS senescence and various neurodegenerative conditions are covered in considerable detail. III. Experimental Models of Astrocyte Senescence: Implications for Neurodegenerative ! Disease. In this final section, experimental approaches to the delineation of the role of astroglia in brain aging and degeneration are described. This book should appeal widely to basic neuroscientists interested in various aspects of the biology of these cells as well as to clinically-oriented investigators concerned with the pathogenesis of the major human neurodegenerative disorders.
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Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting (Computational Neuroscience)
By Eugene M. Izhikevich
Publisher: The MIT Press
Number Of Pages: 457
Publication Date: 2006-11-01
Sales Rank: 77972
ISBN / ASIN: 0262090430
EAN: 9780262090438
Binding: Hardcover
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 5
Total Reviews: 2
Book Description:
In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology.
Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiologica
l properties of neurons but also on their dynamical properties.
The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines.
Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum--or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience.
An additional chapter on synchronization, with more advanced material, can be found at the author's website, Sitemizde bulunan linkleri ziyaretçilerimiz göremezler.
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.
Date: 2007-10-25 Rating: 5
Review:
So you think you are afraid of some math?
This book encapsulates in a single text a large body of knowledge by the author and others over the past two decades on the use of geometrical techniques to both classify and study a large range of single neuron models. While much of this material is known to "experts" in the field, the value of this text is i1) teaching this dynamical systems perspective on single neuron dynamics to generations of new students and 2) educating non-mathematicians into both the utility and use of these theories. Many other texts and papers on this topic leave non-mathematicians "in the dust" shortly after the introduction, but Eugene's excellent use of figures to explain concepts geometrically as well as mathematically enables a PhD student in engineering or quantitative biology to fully appreciate what is going on, not to mention seasoned experimentalists.
Date: 2007-08-10 Rating: 5
Review:
An Interesting Book on Spiking Mechanism and Nonlinear Dynamical System
The goal of Izhikevich's book is to study "the relationship between electrophysiology, bifurcations, and computational properties of neurons." The book also introduces the fundamental concepts of nonlinear dynamical system such as (1) equilibrium, (2) stability, (3) limit cycle attractor, and (4) bifurcations. Actually, it is a good introductory book on applying nonlinear dynamical system on scientific research. The primary subject of the book is the spiking (excitability and bursting) of neurons. By utilizing graphs or phase portraits to demonstrate the mechanism of the spiking generation of neurons, the author makes the readers understand both the spiking mechanism and the concepts of nonlinear dynamical system with ease.
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The Parallel Brain: The Cognitive Neuroscience of the Corpus Callosum (Issues in Clinical and Cognitive Neuropsychology)
By
Publisher: The MIT Press
Number Of Pages: 567
Publication Date: 2002-08-15
Sales Rank: 289368
ISBN / ASIN: 0262240440
EAN: 9780262240444
Binding: Hardcover
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 0
Total Reviews: 0
Book Description:
Hemispheric specialization is involved in every aspect of sensory, cognitive, and motor systems integration. Study of the corpus callosum, the bands of tissue uniting the brain's two hemispheres, is central to understanding neuroanatomy, neurophysiology, and behavior. It also brings the tools of hemispheric specialization to a fundamental problem of cognitive neuroscience: modularity and intermodular communication.
This book summarizes current research on the human corpus callosum. It also provides a comprehensive introduction to cognitive neuroscience. Rather than viewing the field through the various systems of the mind/brain such as perception, action, emotion, memory, language, and problem solving, it takes a case studies approach. Focusing on the central problem of simple reaction time, it examines the most basic possible sequence of perception-decision-action. The task is to press a button with one hand as soon as a patch of light is detected in the peripheral visual field. When the patch appears in the visual field opposite the responding hand, there must be interhemispheric transfer prior to response. But transfer of what--a visual input code? A cognitive decision code? A motor response code? Combining animal models, normal human studies, and clinical evidence, the authors apply anatomical, physiological, and behavioral perspectives to this question. The emerging view is that the corpus callosum consists of many parallel interhemispheric channels for communication and control, and that every transfer channel is context-dependent and modulated by attention.
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28.
Neurotransmitter Transporters: Structure, Function, and Regulation (Contemporary Neuroscience)
By
Publisher: Humana Press
Number Of Pages: 532
Publication Date: 2002-05-15
Sales Rank: 1558487
ISBN / ASIN: 0896039455
EAN: 9780896039452
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:
Maarten Reith and his contributors fully update all the material in his widely acclaimed first edition, expanding it to include the important progress made in characterizing the structure, function, regulation, and physiological relevance of each transporter. The new material includes discussions of gene organization and the relationship of polymorphisms of monoamine transporters with a variety of diseases, transgenic animals carrying altered genes for plasma membrane monoamine transporters, and the regulation of transporters by trafficking in relation to their phosphorylation state. Also addressed are transporter imaging techniques that allow in vivo measurement in men and animals, chimera and site-directed mutagenesis of transporters, and transporter electrophysiology. Neurotransmitter Transporters: Structure, Function, and Regulation, Second Edition continues to be the most informative and useful review of the field, allowing comparison between the characteristics of various neurotransmitter transporters and their biological roles in such a way that progress for one transporter can help move the field of another transporter forward.
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In Vivo Optical Imaging of Brain Function (Methods and New Frontiers in Neuroscience)
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Publisher: CRC
Number Of Pages: 280
Publication Date: 2002-05-15
Sales Rank: 1639233
ISBN / ASIN: 0849323894
EAN: 9780849323898
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Average Rating: 0
Total Reviews: 0
Book Description:
The major advantage of in vivo optical techniques is the ability to study many levels of function of the CNS that are inaccessible by other methods. This rapidly expanding field is multidisciplinary in nature and findings have thus far been scattered throughout the literature. In Vivo Optical Imaging of Brain Function reviews the wide variety of optical imaging techniques that have recently emerged for the specific study of activity in the living brain, as well as their application in animal and human brain research. The book describes noninvasive and invasive optical techniques that enable the description of brain function at levels ranging from single neurons to large assemblies comprising of millions of neurons, and thus address issues related to brain activation ranging from neuronal networks to cognition. Each chapter describes the theory, set-up, analytical methods, and examples of experiments that highlight the advantages of a particular imaging method. Moreover, the authors present technical details at a level that will encourage researchers to utilize the imaging methods in your laboratory. As this field continues to advance our understanding of brain function, researchers need In Vivo Optical Imaging of Brain Function to keep abreast of the latest developments in this exciting area of study.
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Pathogenesis of Neurodegenerative Disorders (Contemporary Neuroscience)
By
Publisher: Humana Press
Number Of Pages: 304
Publication Date: 2001-06-01
Sales Rank: 3297208
ISBN / ASIN: 0896038386
EAN: 9780896038387
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:
In this groundbreaking book, leading experts detail the cellular and molecular cascades that cause selective degeneration of neuronal populations, and illuminate those genetic and environmental factors that are critical to the facilitation or suppression of the neuropathologic processes. Working from studies of human patients, as well as from cell culture and animal models, the authors demonstrate a heretofore unrecognized convergence of the causative pathogenetic mechanisms for clinically distinct neurological disorders. At center stage are the biochemical and molecular cascades that will ultimately lead to neuronal death-cascades involving oxyradical production, aberrant regulation of cellular ion homeostasis, activation of specific proteases, and activation of a stereotyped sequence of events involving mitochondial dysfunction. Individual chapters examine how these mechanisms-along with genetic and environmental factors-operate in Alzheimer's and Parkinson's diseases, Down's syndrome, amyotropic lateral sclerosis, ischemic stroke, spinal cord injury, and Duchenne muscular dystrophy.
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Modeling Neural Development (Developmental Cognitive Neuroscience)
By
Publisher: The MIT Press
Number Of Pages: 336
Publication Date: 2003-09-14
Sales Rank: 1726187
ISBN / ASIN: 0262220660
EAN: 9780262220668
Binding: Hardcover
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 0
Total Reviews: 0
Book Description:
This original and timely collection is one of the first books to study neural development using computational and mathematical modeling. Modeling provides precise and exact ways of expression, which allow us to go beyond the insights that intuitive or commonsense reasoning alone can yield. Most neural modeling focuses on information processing in the adult nervous system; Modeling Neural Development shows how models can be used to study the development of the nervous system at different levels of organization and at different phases of development, from molecule to system and from neurulation to cognition. The formal models described can give structure and meaning to complex phenomena and data, create and explore new hypotheses, and guide further research.
The book's fourteen chapters follow loosely the chronology of neural development. Chapters 1 and 2 study the very early development of the nervous system, discussing gene networks, cell differentiation, and neural tube development. Chapters 3-5 examine neuronal morphogenesis and neurite outgrowth. Chapters 6-8 study different aspects of the self-organization of neurons into networks. Chapters 9-12 cover refinement of connectivity and the development of specific connectivity patterns. Chapters 13 and 14 focus on some of the functional implications of morphology and development.
The science of studying neural development by computational and mathematical modeling is relatively new; this book, as Dale Purves writes in the foreword, "serves as an important progress report" in the effort to understand the complexities of neural development.
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Animal Models of Cognitive Impairment (Frontiers in Neuroscience)
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Publisher: CRC
Number Of Pages: 400
Publication Date: 2006-06-22
Sales Rank: 1867048
ISBN / ASIN: 0849328349
EAN: 9780849328343
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Average Rating: 0
Total Reviews: 0
Book Description:
The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications. The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer's, schizophrenia, and ADHD. Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.
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Clusterin in Normal Brain Functions and During Neurodegeneration (Neuroscience Intelligence Unit)
By Caleb E. Finch
Publisher: LANDES BIOSCIENCE PUBLISHERS
Number Of Pages: 123
Publication Date: 1999-03-15
Sales Rank: 5762043
ISBN / ASIN: 1570595836
EAN: 9781570595837
Binding: Hardcover
Manufacturer: LANDES BIOSCIENCE PUBLISHERS
Studio: LANDES BIOSCIENCE PUBLISHERS
Average Rating: 0
Total Reviews: 0
Book Description:
Clusterin is a multifunctional protein which was independently discovered by more than ten different research groups in the 1980s. New roles of clusterin in brain functions have come to llight which are summarized here by the researchers involved. Recent discoveries include a unique lipoprotein particle containing clusterin and apoE secreted by astrocytes, and the ability of clusterin to promote neurotoxic activities of the amyloid beta peptide, but also to be neuroprotective. Also included is recent information about clusterin and Alzheimer's disease. In all, this is a comprehensive and up-to-date review of clusterin in the brain.
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Cell Therapy, Stem Cells and Brain Repair (Contemporary Neuroscience)
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Publisher: Humana Press
Number Of Pages: 408
Publication Date: 2006-09-01
Sales Rank: 1362762
ISBN / ASIN: 1588295028
EAN: 9781588295026
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:
Cell Therapy, Stem Cells, and Brain Repair reviews the most compelling treatments for neurodegenerative diseases, disorders, and injuries, including Parkinson's disease, Huntington's disease, traumatic brain injury, and stroke. Covering the history of cell therapy and neural transplantation, it also focuses on stem cells, including embryonic, bone marrow, and umbilical cord blood, as well as other investigative sources. This compilation explicates previous cornerstones and milestones of neurological cellular therapy, which have provided a foundation for modern stem cell research.
In Cell Therapy, Stem Cells, and Brain Repair, the challenges and current direction of cellular research are described in great detail. Modern techniques involving certain subsets of cell populations are also explained. In addition, the ongoing discovery of stem cell sources for cell therapy is discussed, while expounding upon clinical applications for cellular therapeutic brain repair as certain cells become increasingly promising.
Explaining the field of cell therapy from a scientific, clinical, and ethical perspective, Cell Therapy, Stem Cell, and Brain Repair is essential reading for neurologists, scientists, and clinicians looking to stay on the cutting-edge of regenerative medicine.
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By
Publisher: Humana Press
Number Of Pages: 440
Publication Date: 2003-01-07
Sales Rank: 498602
ISBN / ASIN: 158829045X
EAN: 9781588290458
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:
A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation. Comprehensive and up-to-date, Genetics and Genomics of Neurobehavioral Disorders integrates the molecular, genomic, neuropsychological, and neurobehavioral factors that produce learning disabilities and mental retardation into a coherent framework for the understanding and assessment of neurobehavioral disorders.
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The New Cognitive Neurosciences: Second Edition
By
Publisher: The MIT Press
Number Of Pages: 1276
Publication Date: 1999-11-26
Sales Rank: 588497
ISBN / ASIN: 0262071959
EAN: 9780262071956
Binding: Hardcover
Manufacturer: The MIT Press
Studio: The MIT Press
Average Rating: 4.5
Total Reviews: 5
Book Description:
The first edition of The Cognitive Neurosciences helped to define the field. The second edition reflects the many advances that have taken place-particularly in imaging and recording techniques. From the molecular level up to that of human consciousness, the contributions cover one of the most fascinating areas of science--the relationship between the structural and physiological mechanisms of the brain/nervous system and the psychological reality of mind. The majority of the chapters in this edition of The Cognitive Neurosciences are new, and those from the first edition have been completely rewritten and updated.
This major reference work is now available online as part of MIT CogNet, The Cognitive and Brain Sciences Community online.
Sections and section editors:
- Plasticity - Ira B. Black
- Development - Pasko Rakic
- Sensory Systems - J. Anthony Movshon and Colin Blakemore
- Motor - Emilio Bizzi
- Attention - Michael I. Posner
- Memory - Endel Tulving
- Language - Willem J. M. Levelt
- Thought and Memory - Edward E. Smith and Stephen M. Kosslyn
- Emotion - Joseph E. LeDoux
- Evolution - Leda Cosmides and John Tooby
- Consciousness - Daniel L. Schacter
Date: 2003-02-01 Rating: 5
Review:
Excellent Review
I am a neurologist. This is the single best book I have read for providing the physiological and anatomical basis for human cognitive behavior. Each chapter is written by an outstanding neuroscientist.
Date: 2002-11-03 Rating: 2
Review:
Not the editorial quality I expected
I checked this book out from our library to see if it would meet my needs as an in-depth introduction and more to the neurosciences. I have a number of MIT press/Bradford books and expected quite a bit from this one. I was impressed with the breadth and range of topics and the quality of scholarship, but the incredible number of typos, particularly in the second section, left me steamed. Those poor authors who had the spelling of their names butchered in print have my sympathy. These typos include some in the diagrams, which lead to confusion. I expect a better quality of editing from a large professional university press. I bought Principles of Neuroscience (Kandel) instead. My advice would be to check out a copy of the Gazzaniga from your library and go over it to see if it is acceptable to you before you spend [...] on it.
Date: 2002-10-04 Rating: 5
Review:
Absolutely spectacular achievement
I think I can claim to be probably the only clinical neurologist who has read both this book and its first edition cover to cover, which really reflects the fascination of the articles more than incredible compulsivity on my part. The book is divided into 11 sections--development, plasticity, sensory systems, motor systems, attention, memory, language, higher cognitive functions, emotion, evolution, and consciousness, with anywhere from 8-15 articles in each section (total 94 chapters!), averaging around 15 pages each, and a helpful introduction written by an expert for the sections. There are also a large number of color illustrations. For the most part, the articles are very clearly written reviews, and would be appropriate for the upper undergraduate or graduate level student. The emphasis is obviously more on neuroscience than on clinical medicine, though helpful correlates to neurological patients can be found in many chapters. Michael Gazzaniga has once again done a masterful job in assembling contributors, and it is wonderful to see how much the field has advanced since the first edition of this book was published in 1995. For anyone with more than a casual interest in the field, this book is a MUST HAVE!!
Date: 2001-03-22 Rating: 5
Review:
Great Book, Not an introduction to the field
I am a freshman in High School and after taking a semester course in Biology Honors and a little guidance from my teacher I set out to do my final human anatomy project on how drugs affect the synaptic regions in nerve cells. Using this book and the Internet i completed the project successfully. The thing about this book is that if you already don't have some understanding of the nervous system, this book may be confusing, yet if you want the latest in the field and not to much history and coverage on the supposed "Mind-Body Problem" get this book. This book is a great text for showing the cell processes and overall nervous system.If you just want a basic understanding of how the nervous system works, get another book, yet if you want to comprehend and do some nice research papers i would recommend this book. This book is a compilation of most the research in the cognitive neurosciences and is in depth and comprehensive as books get. Sure its size and weight may have caused some back strain when in my bookbag, but it was worth it. Check your library for this book before you pay out if you just need it for a paper or project, but if you want to do some learning like I did then buy it.
Date: 1999-04-11 Rating: 5
Review:
The Cognitive Neurosciences
The Cognitive Neurosciences by M.S. Gazzaniga is an exhaustive (and I mean exhaustive) collection of articles representing major theories in each field of cognitive neuroscience. The book focuses on cognitive neuroscience as opposed to something like neuropsychopharmaco
logy or neuroanatomy. It also weighs a ton and a paperback version would be most welcome. Being comprehensive, there is a good deal of depth, but not the kind of depth you'd see in a text on a specific area (e.g., memory). That being said, this is the high-mark for this kind of comprehensive book. My favorite book in the area. Stephen Cox
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37. Cerebral Signal Transduction: From First to Fourth Messengers (Contemporary Neuroscience)
By
Publisher: Humana Press
Number Of Pages: 428
Publication Date: 2000-03-15
Sales Rank: 2368345
ISBN / ASIN: 0896036081
EAN: 9780896036086
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:
A team of leading experts comprehensively review and synthesize the most recent advances in our understanding of the role of cerebral signaling in neuronal and cerebral function. The authors emphasize the functional role of the various signaling pathways in memory, apoptosis and degeneration, depression, and drug dependence in both health and diseased states. By taking full advantage of the newfound ability to selectively remove, reduce, or enhance specific components of the signaling pathways, the investigators writing here illuminate the varied signaling cascades, their crosstalk, and the many possibilities for changes in gene expression underlying long-term changes in brain function. Cutting-edge and comprehensive, Cerebral Signal Transduction: From First to Fourth Messengers advances our understanding of the mechanistic underpinnings of complex behavioral processes and clinically relevant brain diseases. A major contribution to the development of the novel pharmacotherapeutic
s targeting downstream events in the cascade of second, third, and fourth messengers, it will serve experimental and clinical neuroscientists as the best and most complete guide to neuronal signaling.
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